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KMID : 0617320030120010224
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Journal of Pharmacetical Sceiences Ewha Womans University
2003 Volume.12 No. 1 p.224 ~ p.226
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Synthesis of Halogenated 9-(Dihydroxycyclopent-4´-enyl) Adenines and Their Inhibitory Activities Against S-Adenosylhomocysteine Hydrolase
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Jeong, Lak Shin
Park, Jae Gyu/Choi, Won Jun/Moon, Hyung Ryong/Lee, Kang Man/Kim, Hea Ok/Kim, Hee-Doo
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Abstract
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Novel halovinyl analogues of neplanocin A without 4´-hydroxymethyl group were easily synthesized starting from D-ribose via cyclopentenone 5 as a key intermediate and their inhibitory activity against SAH hydrolase was assayed.
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